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For information on the foundation or to make a donation, please visit the Hope For Caroline website Hope For Caroline is a 501(c)3 organization raising awareness and funding research for DIPG.

What is a DIPG?
A Diffuse Intrinsic Pontine Glioma (DIPG) is a malignant tumor located in the pons or middle portion of the brain stem.  The brain stem, located at the bottom of the brain, connects the brain to the spinal cord.  These tumors are diffusely infiltrating, growing amidst the nerves, rendering surgical removal impossible.  Glioma is general term describing a tumor arising from the glial or supportive tissue that helps keep the neurons or “thinking cells” in place and functioning.  The brain stem contains all the “wires” converging from the brain to the spinal cord as well as important structures involved in eye movement and coordination, face and throat muscle control, and sensation.
Approximately 150 to 200 cases of DIPG are diagnosed annually.  The median age at diagnosis is 5 to 9 years old but tumors can develop at any age in childhood.  DIPGs occur with equal frequency among boys and girls, and there are no known factors or conditions that predispose a child to developing DIPG.

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